I now advocate for deprescribing gabapentin when patients do not achieve adequate pain relief for chronic neuropathic pain at a cumulative daily dose of 1800 mg. Instead, I consider pregabalin as a substitute for gabapentin in patients with inadequate pain control rather than further dose escalations.
Heart failure is the third leading cause of hospitalization in Canada and leads to readmission in 1 in 5 patients within 30 days after discharge. Iron deficiency (with or without anemia) is an important comorbidity in patients with HF and is associated with worse outcomes. Assess iron deficiency for all patients with HFrEF and HFmrEF admitted for acute HF.
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