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By Dr. Breay Paty on February 18, 2015
Nausea can be a common side effect of GLP-1 receptor agonist, which can sometimes be dose limiting. However, this usually improves with time. As a new class of agents, evidence for the long-term safety of incretins is still emerging. Most of the safety questions involve cardiovascular (CV) risk, as well as pancreatitis and pancreatic cancer.
By Dr. Sandra Sirrs on February 4, 2013
Ultrasound can be a powerful tool in distinguishing thyroid nodules with malignant potential from benign ones. Thyroid nodules found on physical examination are common. Fewer than 5% of these nodules are malignant.
By Dr. Breay Paty on January 23, 2012
These oral agents, administered once daily, augment endogenous GLP-1, resulting in an A1C reduction of 0.5 – 0.9%. Since GLP-1 does not directly stimulate insulin, they have the advantage of not promoting hypoglycemia or weight gain.
By Dr. Breay Paty on June 20, 2011
Recent studies suggest that the relationship between glucose control (A1C) and cardiovascular disease is more complex than we may have realized.
By Dr. Graeme Wilkins on March 14, 2011
Overt hypothyroidism is seen in 0.3 to 0.5% of the general population and subclinical hypothyroidism (high TSH and normal free T4) is seen in 2-3%. Thyroid antibodies are identified in 5-15% of women.
By Dr. Breay Paty on April 15, 2010
Since their introduction, certain contraindications and side effects have been well known, including worsening heart failure, edema (including macular edema) and weight gain.