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» This Changed My Practice » Antibiotics

Antibiotics

Physician-Patients

Management of Helicobacter pylori in 2023: who should be tested, treated, and how

By Dr. Sander Veldhuyzen van Zanten on August 9, 2023

Helicobacter pylori (H. pylori) continues to be an important pathogen, associated with peptic ulcer disease, dyspepsia, and gastric cancer. The conventional triple combination of a PPI, clarithromycin, and either amoxicillin or metronidazole is no longer recommended because its success rates have decreased to less than 60%. The recommended first-line therapy is concomitant therapy (PPI, clarithromycin, amoxicillin, and metronidazole) and second-line therapy is bismuth-based therapy (PPI, bismuth, metronidazole, and tetracycline).

Bugs and Drugs App

Bugs & Drugs guide to antimicrobial therapy

By Dr. Karin Kausky, Dr. Tracy Monk, and Daniela Michel, MPH on January 11, 2023

Antimicrobial resistance is recognized as a top public health threat and is estimated to be directly responsible for 5,400 deaths and $1.4 billion in health care costs in Canada in 2018 which underlines the critical importance of wise prescribing of antibiotics. Every time I prescribe an antibiotic now, I check the Bugs & Drugs guidelines via PathwaysBC.ca.

Duration of antimicrobial therapy for common infections in primary care

Duration of antimicrobial therapy for common infections in primary care

By Dr. Kevin Afra, Maggie Wong, PharmD, Tim T.Y. Lau, PharmD, and Dr. Victor Leung on August 15, 2022

Antibiotic treatment duration decision-making is fundamentally a balance of expected benefit and harm. Anchoring our expectations of benefit and harm with the most current literature can better inform clinical decision-making. The harms of antibiotics are often underappreciated. Shorter treatment durations are just as effective as longer durations for a wide range of common infections.

Update on the guidelines for Subacute Bacterial Endocarditis (SBE) prophylaxis

Update on the guidelines for Subacute Bacterial Endocarditis (SBE) prophylaxis

By Dr. Natasha Press on March 5, 2014

The most recent AHA guidelines (2007) have limited antibiotic prophylaxis to those patients at highest-risk for developing endocarditis and who are undergoing high-risk invasive procedures.

MRSA skin and soft tissue infections

By Dr. Natasha Press on April 16, 2010

A 32 year old woman, otherwise healthy, presented with a “spider-bite”. On exam, she had a tender abscess on her buttock. It was associated with some surrounding cellulitis but no fever or other systemic features.


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